Founder & CEO
We study how the structure of mitochondria and their contacts with organelles translate to function and/or to disease etiology.
Our research in the Hoek laboratory focuses on the unique regenerative capabilities of the liver and how they are distinctively regulated by mitochondrial calcium signaling and alcohol metabolism.
In the Seifert lab we study the regulation of mitochondrial substrate metabolism as well as the nature of cellular ‘stress’ responses triggered in vivo by mammalian mitochondrial dysfunction.
In the Tigano lab we perform foundational research in the field of mitochondrial disorders and stress signaling.
Raphael Rubin Professor of Medicine
Our study focuses on the roles of mitochondrial signaling and dynamics in health and disease.
My lab studies the regulation of calcium release by IP3 receptors and the uptake of calcium by the mitochondrial calcium uniporter.
Professor of Medicine
Our research vision is to improve health and cure disease through toning mitochondrial energetics, Ca2+, and redox signaling
Technology Development Director
I direct the MitoCare efforts toward developing innovative applications of technology to problems in mitochondrial biology, from data acquisition to analysis.