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At MitoCare we also focus on the diagnostics and the pathogenesis of disorders driven by mitochondrial dysfunction.
MitoCare investigators study the consequences of mitochondrial dysfunction at the organismal level (in vivo) and in vitro models.
MURINE in vivo models
Chronic Alcoholic Rat
High Fat Diet Mouse
MICU2 Knock Out
Miro1 Knock Out
PATIENT DERIVED IN VITRO modelS
Fibroblasts and Lymphoblasts
PiC Loss of Function
MICU1 and MICU2 Loss of Function
Autosomal Dominant Optic Atrophy OPA1 mutations
MERRF and MELAS Fibroblasts
"Common Deletion" Fibroblasts
AD HOC IN VITRO modelS
Using cutting-edge CRISPR Cas9 genetic engineering, MitoCare researchers create new relevant models every day.
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